Dr. Sanjeev Kumar Sharma offers advanced bone marrow and stem cell transplant care in Delhi-NCR, with personalised transplant protocols; autologous, allogeneic, and haploidentical for leukemia, lymphoma, multiple myeloma, and complex or high-risk hemato-oncology cases.
Connect with Dr. Sanjeev Kumar Sharma for personalised bone marrow transplant care
Bone marrow transplant (BMT) replaces damaged or diseased bone marrow with healthy stem cells to treat blood cancers like leukemia, lymphoma, and multiple myeloma. It can be autologous (using the patient's own cells) or allogeneic (using a donor's cells). Dr. Sanjeev Kumar Sharma, Principal Director, Hemato-Oncology & BMT at Paras Health, Gurugram, has performed 1,000+ bone marrow transplants across both types. This page covers how BMT works, the different types available, cost, and recovery.
For patients with certain blood cancers and bone marrow disorders, a bone marrow transplant offers the chance at long-term remission or cure; especially when standard treatments like chemotherapy alone aren't enough. A bone marrow transplant works by replacing unhealthy bone marrow with healthy stem cells, allowing the body to rebuild its ability to produce normal blood cells.
Dr. Sanjeev Kumar Sharma, Principal Director, Hemato-Oncology & BMT at Paras Health Gurugram, is among the leading bone marrow transplant specialists in Delhi NCR, with over 20 years of experience and 1,000+ transplants performed. This page walks you through the types of bone marrow transplant available, how the procedure works, associated risks, and what recovery looks like.
A bone marrow transplant (BMT), also called a stem cell transplant (SCT), is a definitive treatment for many hematological diseases. It works by replacing damaged or cancerous bone marrow with healthy stem cells, restoring the body's ability to produce normal blood cells.
There are two main types. Autologous bone marrow transplant and Allogeneic bone marrow transplant. Autologous uses the patient's own stem cells, so no donor is needed, commonly used for multiple myeloma and lymphoma. Whereas, Allogeneic bone marrow transplant requires a matched donor, typically used for acute leukemia, aplastic anemia, and thalassemia.
Donation carries little to no risk to the donor, and peripheral blood stem cells can now be collected much like a routine platelet (SDP) donation.
BMT is commonly recommended for leukemia, lymphoma, multiple myeloma, and high-risk myelodysplastic syndrome, especially when chemotherapy alone isn't enough; offered for eligible patients across Delhi NCR and Gurugram.
There are two main approaches to bone marrow transplant, and the right one depends on your specific diagnosis and available donor options. Dr. Sanjeev Kumar Sharma offers both autologous and allogeneic bone marrow transplant in Gurugram, guiding patients to the approach best suited to their condition.
The patient's own healthy stem cells are collected and stored before chemotherapy. After growth factor (GCSF) injections for 4-5 days, the cells are harvested through stem cell apheresis. Once high-dose chemotherapy is complete, the harvested cells are reinfused. Recovery typically takes 2-3 weeks before discharge. Since the cells come from the patient's own body, rejection risk is lower and recovery is often faster; commonly used for multiple myeloma and lymphoma.
Doctors monitor the patient daily as the new stem cells settle in and start making healthy blood again, giving support if needed. Once stable, the patient is discharged with regular follow-ups to track recovery.
Healthy stem cells come from a donor, typically the approach for leukemia, aplastic anemia, and thalassemia. Three main types:
Bone marrow transplant is a life-saving procedure that has helped cure millions of people worldwide with otherwise incurable blood disorders, but like any major treatment, it carries some risks. These include:
An acute or chronic reaction where donor stem cells respond against the recipient's body; relevant to allogeneic transplants only, since autologous transplants use the patient's own cells and don't carry this risk.
A temporary drop in immunity during recovery increases infection risk, particularly in the weeks following the conditioning regimen, before blood counts fully recover.
In rare cases, the transplant may not take hold, or the underlying disease may return. This is closely tracked through follow-up testing as part of monitoring bone marrow transplant success rate and long-term outcomes.
Step-by-step process
Specialist assesses health and disease status to confirm eligibility and transplant type.
HLA typing matches family members, or extends to a MUD registry or haploidentical donor if needed.
Growth factor injections precede harvesting via apheresis, followed by chemotherapy (± radiation) to clear diseased marrow.
Healthy stem cells are infused into the bloodstream; this is Day 0.
Over 2-3 weeks, new cells settle into the marrow and start producing healthy blood. Follow-ups track recovery and early GVHD signs.
Every bone marrow transplant in Delhi NCR begins with a detailed evaluation to ensure both patient and donor are ready;a key factor in overall bone marrow transplant success rate.
Patients seeking bone marrow transplant in Delhi NCR benefit from advanced, well-supported protocols at every stage, offered by Dr. Sanjeev Kumar Sharma, a trusted BMT specialist in Gurugram.
What to Expect After Transplant
Recovery varies by patient, but most gradually regain strength as the care team monitors progress closely.
Engraftment & Immune Recovery Timeline
New stem cells usually settle in within 2-3 weeks, with the immune system continuing to rebuild over the following months.
Managing GVHD & Complications
For donor transplant patients, regular checkups help catch issues like GVHD or infections early.
Follow-Up & Long-Term Monitoring
Ongoing blood tests and follow-ups track recovery and long-term outcomes.
The cost of bone marrow transplant in Gurgaon depends on several factors specific to each patient's diagnosis and treatment plan. Key factors include:
Since every patient's journey is different, we recommend a consultation with our stem cell transplant specialist for a personalized cost estimate based on your diagnosis and transplant type.
Dr. Sanjeev Kumar Sharma, Principal Director of Hemato-Oncology & BMT at Paras Health, Gurugram, brings over 20 years of clinical experience to every patient's transplant journey. As a leading stem cell transplant specialist, he has helped patients across Gurugram and Delhi NCR achieve long-term, evidence-based outcomes.
Everything you need to know before your consultation
It replaces damaged or cancerous bone marrow with healthy stem cells, helping the body produce normal blood cells again.
They refer to the same procedurestem cells can be collected from bone marrow, peripheral blood, or cord blood.
Autologous uses the patient's own stem cells; allogeneic uses cells from a matched donor.
Patients with leukemia, lymphoma, multiple myeloma, thalassemia, aplastic anemia, sickle cell disease, or high-risk MDS, based on medical evaluation.
Through HLA typing, starting with siblings, then extending to unrelated donor registries or half-matched family members if needed.
Success rates vary by disease type, stage, and patient factors, with many achieving long-term remission.
Cost depends on transplant type, donor search, hospital stay, and any complications; best discussed during consultation.
Engraftment typically takes 2-3 weeks, with full immune recovery continuing over several months.
Possible risks include GVHD (in allogeneic transplants), infections, and rare cases of rejection or relapse.
Dr. Sanjeev Kumar Sharma offers advanced bone marrow transplant care at Paras Health, Gurugram.
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